SLC22A2 antibody (N-Term)

Catalog No. ABIN2781589

Product Details anti-SLC22A2 Antibody

Target: SLC22A2 (Solute Carrier Family 22 (Organic Cation Transporter), Member 2 (SLC22A2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MPTTVDDVLE HGGEFHFFQK QMFFLLALLS ATFAPIYVGI VFLGFTPDHR

Predicted Reactivity: Cow: 83%, Dog: 83%, Guinea Pig: 83%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 83%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against SLC22A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC22A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 555 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC22A2 antibody (ABIN2781589)

Pelis, Suhre, Wright: "Functional influence of N-glycosylation in OCT2-mediated tetraethylammonium transport." in: American journal of physiology. Renal physiology, Vol. 290, Issue 5, pp. F1118-26, (2006) (PubMed).

Target Details for SLC22A2

Target: SLC22A2 (Solute Carrier Family 22 (Organic Cation Transporter), Member 2 (SLC22A2))

Alternative Name: SLC22A2 (SLC22A2 Products)

Synonyms: OCT2 antibody, Oct2 antibody, Orct2 antibody, OCT2r antibody, rOCT2 antibody, Pou2f2 antibody, OCT2P antibody, oct1 antibody, wu:fc01b11 antibody, zgc:64076 antibody, slc22a2 antibody, solute carrier family 22 member 2 antibody, solute carrier family 22 (organic cation transporter), member 2 antibody, POU class 2 homeobox 2 antibody, solute carrier family 22 (organic cation transporter), member 2 L homeolog antibody, SLC22A2 antibody, Slc22a2 antibody, POU2F2 antibody, LOC521027 antibody, slc22a2 antibody, slc22a2.L antibody

Background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A2 is one of the three similar cation transporters. SLC22A2 contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC32628, OCT2
Protein Interaction Partner: AGO3, CST9L, LSM4, HYAL3, SUMO2, GTF2B, EXT2, ETV5, POU2AF1,
Protein Size: 555

Molecular Weight: 62 kDa

Gene ID: 6582

NCBI Accession: NM_003058, NP_003049

UniProt: O15244