SLC39A6 antibody (Middle Region)

Catalog No. ABIN2781630

Product Details anti-SLC39A6 Antibody

Target: SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Sheep, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RSCLIHTSEK KAEIPPKTYS LQIAWVGGFI AISIISFLSL LGVILVPLMN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC39A6. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC39A6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 433 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC39A6 antibody (ABIN2781630)

Trokovic, Pöllänen, Porola, Stegaev, Hetzel, Tivesten, Engdahl, Carlsten, Forsblad-dElia, Fagman, Lagerquist, Konttinen: "Exosomal secretion of death bullets: a new way of apoptotic escape?" in: American journal of physiology. Endocrinology and metabolism, Vol. 303, Issue 8, pp. E1015-24, (2012) (PubMed).

Target Details for SLC39A6

Target: SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))

Alternative Name: SLC39A6 (SLC39A6 Products)

Synonyms: liv1 antibody, wu:fc25a09 antibody, ZIP6 antibody, Ermelin antibody, LIV-1 antibody, solute carrier family 39 (zinc transporter), member 6 antibody, solute carrier family 39 member 6 antibody, solute carrier family 39 (metal ion transporter), member 6 antibody, slc39a6 antibody, SLC39A6 antibody, Slc39a6 antibody

Background: Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters.
Alias Symbols: LIV-1
Protein Interaction Partner: SUMO1, UBC, NEDD8, SPP1, KDM5B,
Protein Size: 433

Molecular Weight: 48 kDa

Gene ID: 25800

NCBI Accession: NM_001099406, NP_001092876

Pathways: Transition Metal Ion Homeostasis