TTYH1 antibody (N-Term)

Catalog No. ABIN2781896

Product Details anti-TTYH1 Antibody

Target: TTYH1 (Tweety Homolog 1 (TTYH1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTYH1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GAPPGYRPSA WVHLLHQLPR ADFQLRPVPS VFAPQEQEYQ QALLLVAALA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TTYH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TTYH1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 450 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TTYH1 antibody (ABIN2781896)

Suzuki, Mizuno: "A novel human Cl(-) channel family related to Drosophila flightless locus." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22461-8, (2004) (PubMed).

Target Details for TTYH1

Target: TTYH1 (Tweety Homolog 1 (TTYH1))

Alternative Name: TTYH1 (TTYH1 Products)

Synonyms: 4930459B04Rik antibody, 6330408P11Rik antibody, tty antibody, TTYH1 antibody, ttyh1-A antibody, tweety family member 1 antibody, tweety family member 1 L homeolog antibody, Protein tweety homolog 1 antibody, Ttyh1 antibody, TTYH1 antibody, ttyh1.L antibody, ttyh-1 antibody

Background: TTYH1 is a member of the tweety family of proteins. Members of this family function as chloride anion channels. TTYH1 functions as a calcium (2+)-independent, volume-sensitive large conductance chloride (-) channel. This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: -
Protein Interaction Partner: UBC,
Protein Size: 450

Molecular Weight: 49 kDa

Gene ID: 57348

NCBI Accession: NM_020659, NP_065710

UniProt: Q9H313