B4GALT2 antibody (Middle Region)

Catalog No. ABIN2781899

Product Details anti-B4GALT2 Antibody

Target: B4GALT2 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 2 (B4GALT2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio), Goat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B4GALT2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NRISLTGMKI SRPDIRIGRY RMIKHDRDKH NEPNPQRFTK IQNTKLTMKR

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 91%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against B4GALT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human B4GALT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 372 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for B4GALT2

Target: B4GALT2 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 2 (B4GALT2))

Alternative Name: B4GALT2 (B4GALT2 Products)

Synonyms: B4Gal-T2 antibody, B4Gal-T3 antibody, beta4Gal-T2 antibody, Ggtb2 antibody, b4gal-t1 antibody, b4galt2 antibody, beta4gal-t1 antibody, cdg2d antibody, ggtb2 antibody, gt1 antibody, gtb antibody, b4gal-t2 antibody, beta4gal-t2 antibody, b4Gal-T2 antibody, si:ch211-261p7.4 antibody, CKII antibody, beta-1,4-galactosyltransferase 2 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, gene 2 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 S homeolog antibody, B4GALT2 antibody, B4galt2 antibody, b4galt1.2 antibody, b4galt2.S antibody, b4galt2 antibody

Background: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: B4Gal-T2, B4Gal-T3, beta4Gal-T2
Protein Interaction Partner: PFDN6,
Protein Size: 372

Molecular Weight: 42 kDa

Gene ID: 8704

NCBI Accession: NM_001005417, NP_001005417

UniProt: O60909

Pathways: Glycosaminoglycan Metabolic Process