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SIL1 antibody (N-Term)

SIL1 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782036
  • Target See all SIL1 Antibodies
    SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))
    Binding Specificity
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 24
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse
    Host
    • 21
    • 2
    • 1
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    This SIL1 antibody is un-conjugated
    Application
    • 20
    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KETKAEEELD AEVLEVFHPT HEWQALQPGQ AVPAGSHVRL NLQTGEREAK
    Predicted Reactivity
    Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SIL1. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SIL1
    Top Product
    Discover our top product SIL1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 461 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))
    Alternative Name
    SIL1 (SIL1 Products)
    Synonyms
    1810057E01Rik antibody, AI042831 antibody, wz antibody, BAP antibody, MSS antibody, ULG5 antibody, endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae) antibody, SIL1 nucleotide exchange factor L homeolog antibody, SIL1 nucleotide exchange factor antibody, Sil1 antibody, sil1.L antibody, SIL1 antibody
    Background
    SIL1 is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in its gene have been associated with Marinesco-Sjogren syndrome.This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
    Alias Symbols: BAP, MSS, ULG5
    Protein Interaction Partner: UBQLN1, FBXO6, UBC, SMAD9, CCND3, HSPA5,
    Protein Size: 461
    Molecular Weight
    49 kDa
    Gene ID
    64374
    NCBI Accession
    NM_022464, NP_071909
    UniProt
    Q9H173
    Pathways
    Unfolded Protein Response, SARS-CoV-2 Protein Interactome
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