SIL1 antibody (SIL1 Homolog, Endoplasmic Reticulum Chaperone (S. Cerevisiae)) (C-Term)

Details for Product anti-SIL1 Antibody No. ABIN2782037, Supplier: Log in to see
Antigen
  • 1810057E01Rik
  • AI042831
  • wz
  • BAP
  • MSS
  • ULG5
  • endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
  • SIL1 nucleotide exchange factor L homeolog
  • SIL1 nucleotide exchange factor
  • Sil1
  • sil1.L
  • SIL1
Alternatives
anti-Human SIL1 antibody for ELISA
Epitope
C-Term
17
10
9
6
4
3
3
2
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
76
20
6
2
2
2
2
2
1
1
1
Host
Rabbit
37
20
19
Clonality
Polyclonal
Conjugate
This SIL1 antibody is un-conjugated
4
4
3
3
3
3
Application
Western Blotting (WB)
72
37
33
18
16
13
5
2
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human SIL1
Blocking Peptide Blocking peptide for this product available: ABIN983748
Sequence KLQQYRQVHL LPGLWEQGWC EITAHLLALP EHDAREKVLQ TLGVLLTTCR
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against SIL1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Plasmids, Primers & others Plasmids, Primers & others SIL1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name SIL1 (SIL1 Antibody Abstract)
Background SIL1 is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in its gene have been associated with Marinesco-Sjogren syndrome.This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
Alias Symbols: BAP, MSS, ULG5
Protein Interaction Partner: UBQLN1, FBXO6, UBC, SMAD9, CCND3, HSPA5,
Protein Size: 461
Molecular Weight 49 kDa
Gene ID 64374
NCBI Accession NM_001037633, NP_001032722
UniProt Q9H173
Pathways Unfolded protein response
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 461 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-SIL1 Homolog, Endoplasmic Reticulum Chaperone (S. Cerevisiae) (SIL1) (C-Term) antibody (ABIN2782037) WB Suggested Anti-SIL1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Posi...
Western Blotting (WB) image for anti-SIL1 Homolog, Endoplasmic Reticulum Chaperone (S. Cerevisiae) (SIL1) (C-Term) antibody (ABIN2782037) WB Suggested Anti-SIL1 antibody Titration: 1 ug/mL Sample Type: Human heart
Western Blotting (WB) image for anti-SIL1 Homolog, Endoplasmic Reticulum Chaperone (S. Cerevisiae) (SIL1) (C-Term) antibody (ABIN2782037) Host: Rabbit Target Name: SIL1 Sample Type: Human Fetal Heart Antibody Dilution...
Immunohistochemistry (IHC) image for anti-SIL1 Homolog, Endoplasmic Reticulum Chaperone (S. Cerevisiae) (SIL1) (C-Term) antibody (ABIN2782037) Rabbit Anti-BAP / SIL1 antibody Formalin Fixed Paraffin Embedded Tissue: Human Adul...
Immunohistochemistry (IHC) image for anti-SIL1 Homolog, Endoplasmic Reticulum Chaperone (S. Cerevisiae) (SIL1) (C-Term) antibody (ABIN2782037) Rabbit Anti-BAP / SIL1 antibody Formalin Fixed Paraffin Embedded Tissue: Human Adul...
Background publications Karim, Parsian, Cleves, Bracey, Elsayed, Elsobky, Parsian: "A novel mutation in BAP/SIL1 gene causes Marinesco-Sjögren syndrome in an extended pedigree." in: Clinical genetics, Vol. 70, Issue 5, pp. 420-3, 2006 (PubMed).

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