ACVR2B antibody (Middle Region)
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- Target See all ACVR2B Antibodies
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Horse, Sheep, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ACVR2B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LCHVAETMSR GLSYLHEDVP WCRGEGHKPS IAHRDFKSKN VLLKSDLTAV
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against ACVR2B. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ACVR2B
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 512 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- Alternative Name
- ACVR2B (ACVR2B Products)
- Synonyms
- ACVR2B antibody, XAR1 antibody, actr-iib antibody, actriib antibody, ACTRIIB antibody, ActR-IIB antibody, HTX4 antibody, ActRIIB antibody, actr2b antibody, actrIIb antibody, wu:fj97d11 antibody, activin A receptor type 2B antibody, activin A receptor type 2B L homeolog antibody, activin A receptor type 2Ba antibody, activin receptor IIB antibody, ACVR2B antibody, acvr2b antibody, acvr2b.L antibody, Acvr2b antibody, acvr2ba antibody
- Background
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Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for
Alias Symbols: ACTRIIB, ActR-IIB, MGC116908, HTX4
Protein Interaction Partner: GDF2, BMP10, INHBA, PEG10, ERBB2IP, HSP90AA1, SMAD7, SMAD6, SMAD2, IGSF1, SYNJ2BP, SNX6, SNX2, TGFBRAP1, GDF11, MSTN, ACVR1B, SNX1, INHBC, GDF5, INHBB, BMP7, BMP2, ENG, BMP6,
Protein Size: 512 - Molecular Weight
- 58 kDa
- Gene ID
- 93
- NCBI Accession
- NM_001106, NP_001097
- UniProt
- Q13705
- Pathways
- Hormone Transport, Cancer Immune Checkpoints
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