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IFNGR2 antibody (Middle Region)

IFNGR2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782679
  • Target See all IFNGR2 Antibodies
    IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
    Binding Specificity
    • 14
    • 10
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 48
    • 11
    • 2
    Human
    Host
    • 42
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 45
    • 5
    Polyclonal
    Conjugate
    • 23
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This IFNGR2 antibody is un-conjugated
    Application
    • 31
    • 20
    • 17
    • 16
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    WEKGGIQQVK GPFRSNSISL DNLKPSRVYC LQVQAQLLWN KSNIFRVGHL
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against IFNGR2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human IFNGR2
    Top Product
    Discover our top product IFNGR2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 337 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

  • Target
    IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
    Alternative Name
    IFNGR2 (IFNGR2 Products)
    Synonyms
    Ifgr2 antibody, Ifgt antibody, AF-1 antibody, IFGR2 antibody, IFNGT1 antibody, interferon gamma receptor 2 antibody, Ifngr2 antibody, IFNGR2 antibody, LOC487739 antibody
    Background
    IFNGR2 is the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: AF-1, IFGR2, IFNGT1
    Protein Interaction Partner: RPL37A, CAMK2D, ELAVL1, DNAJA3, JAK2, IFNG, NR3C1, ANXA5, IFNGR1,
    Protein Size: 337
    Molecular Weight
    35 kDa
    Gene ID
    3460
    NCBI Accession
    NM_005534, NP_005525
    UniProt
    P38484
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