SERPINE1 antibody (serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1) (N-Term)

Details for Product anti-SERPINE1 Antibody No. ABIN2782976, Supplier: Log in to see
Antigen
  • PAI
  • PAI-1
  • PAI1
  • PLANH1
  • SERPINE1
  • si:ch211-138a11.1
  • Planh1
  • PAI1A
  • Pai1
  • Pai1aa
  • Planh
  • RATPAI1A
  • serpin family E member 1
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • serine (or cysteine) peptidase inhibitor, clade E, member 1
  • SERPINE1
  • serpine1.L
  • serpine1
  • Serpine1
Alternatives
anti-Human SERPINE1 antibody for ELISA
Epitope
N-Term
37
18
15
13
11
9
8
8
8
8
5
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
416
129
124
35
12
11
6
5
4
3
3
2
2
2
1
1
Host
Rabbit
264
176
53
26
2
1
Clonality
Polyclonal
Conjugate
This SERPINE1 antibody is un-conjugated
48
34
21
7
7
5
5
5
5
5
5
5
5
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
382
277
205
71
44
35
30
27
27
26
20
17
10
6
5
5
4
4
4
3
2
2
1
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SERPINE1
Blocking Peptide Blocking peptide for this product available: ABIN983583
Sequence VAHLASDFGV RVFQQVAQAS KDRNVVFSPY GVASVLAMLQ LTTGGETQQQ
Predicted Reactivity Cow: 100%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
Characteristics This is a rabbit polyclonal antibody against SERPINE1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SERPINE1 (SERPINE1 Antibody Abstract)
Background SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis.
Alias Symbols: PAI, PAI-1, PAI1, PLANH1
Protein Interaction Partner: SGTB, UBQLN1, SGTA, NOS2, UBQLN4, PSMB1, PSMA3, UBC, LRP1B, ACTN4, LRP2, VTN, PLAU, MMP3, F2, PLAT, SERPINE1, PLG, KRT18, KLK2, IGFBP5, ORM1, ELANE, LRP1,
Protein Size: 402
Molecular Weight 43 kDa
Gene ID 5054
NCBI Accession NM_000602, NP_000593
UniProt P05121
Pathways p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 402 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) (N-Term) antibody (ABIN2782976) WB Suggested Anti-SERPINE1 Antibody Titration: 0.2-1 ug/ml Positive Control: Trans...
Immunohistochemistry (IHC) image for anti-serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) (N-Term) antibody (ABIN2782976) anti-serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) (N-Term) antibody (ABIN2782976) Host: Rabbit Target Name: SERPINE1 Sample Tissue: Mouse Skeletal Muscle Antibod...
Product cited in: Penco, Buscema, Patrosso, Marocchi, Grossi: "New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background." in: BMC bioinformatics, Vol. 9, pp. 254, 2008 (PubMed).

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