THG1L antibody (Middle Region)

Catalog No. ABIN2783150

Product Details anti-THG1L Antibody

Target: THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Horse, Guinea Pig, Cow, Saccharomyces cerevisiae, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THG1L antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DCHINNLYNT VFWALIQQSG LTPVQAQGRL QGTLAADKNE ILFSEFNINY

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 91%, Rabbit: 100%, Rat: 86%, Yeast: 83%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against THG1L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human THG1L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 298 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for THG1L

Target: THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))

Alternative Name: THG1L (THG1L Products)

Synonyms: ICF45 antibody, IHG-1 antibody, 1700121M19Rik antibody, 5730409G07Rik antibody, AA387658 antibody, tRNA-histidine guanylyltransferase 1 like antibody, tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) antibody, tRNA-histidine guanylyltransferase 1-like antibody, THG1L antibody, Thg1l antibody

Background: THG1L adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
Alias Symbols: FLJ11601, FLJ20546, ICF45
Protein Interaction Partner: THG1L, SDCBP, DPP9, SH3GLB1, TPRKB, EEF2K, ARPC1A, ARPC2, TPD52L2, SH3GL1, RANGAP1, PRKAR1B, MTR, HARS, CALU, CALR, WDR92, TP53RK, AARSD1, SH3GLB2, NSUN2, UBC, PLS3, TERF1, ELMOD1,
Protein Size: 298

Molecular Weight: 35 kDa

Gene ID: 54974

NCBI Accession: NM_017872, NP_060342

UniProt: Q9NWX6