NR4A3 antibody (Middle Region)
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- Target See all NR4A3 Antibodies
- NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Horse, Dog, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR4A3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VKVSDFGMAR YVLDDQYTSS SGAKFPVKWC PPEVFNYSRF SSKSDVWSFG
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Characteristics
- This is a rabbit polyclonal antibody against TEC. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TEC
- Top Product
- Discover our top product NR4A3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 631 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))
- Alternative Name
- TEC (NR4A3 Products)
- Synonyms
- CHN antibody, CSMF antibody, MINOR antibody, NOR1 antibody, TEC antibody, AI573420 antibody, NOR-1 antibody, Nor1 antibody, NOR-2 antibody, NR4A3 antibody, Nr4a3 antibody, nuclear receptor subfamily 4 group A member 3 antibody, nuclear receptor subfamily 4, group A, member 3 antibody, NR4A3 antibody, Nr4a3 antibody, nr4a3 antibody
- Background
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The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Alias Symbols: MGC126760, MGC126762, PSCTK4
Protein Interaction Partner: ERBB2, MED28, GRB2, SHC1, FASLG, Nedd4, UBC, IKBKG, STAP1, PIP4K2A, PLK4, PTPN18, PIK3R3, GNA12, SOCS1, PIP5K1A, PTPN21, DOK1, TEC, PLCG2, WAS, BTK, BMX, TP53, PRLR, PLCG1, PIK3R1, LYN, KIT, VAV1, JAK2, JAK1, ARHGEF12, GNA13, RHOA, RAC1, PIK3R2,
Protein Size: 631 - Molecular Weight
- 73 kDa
- Gene ID
- 7006
- NCBI Accession
- NM_003215, NP_003206
- UniProt
- P42680
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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