NEDD9 antibody (Middle Region)

Catalog No. ABIN2784461

Product Details anti-NEDD9 Antibody

Target: NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEDD9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: HPPPQLGQSV GSQNDAYDVP RGVQFLEPPA ETSEKANPQE RDGVYDVPLH

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against NEDD9. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NEDD9

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 834 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NEDD9

Target: NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))

Alternative Name: NEDD9 (NEDD9 Products)

Background: Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers.
Alias Symbols: CAS-L, CASL, HEF1, dJ49G10.2, dJ761I2.1, CAS2, CASS2
Protein Interaction Partner: NFKBIA, NAB2, RFX6, PRR20A, BANP, RBPMS, BCAR3, TRIP6, TRIM27, REL, SMAD1, APP, CRK, UBC, PIK3CA, DIMT1, ELSPBP1, NEDD9, ITCH, CHAT, MICAL1, SH2D3C, SMAD3, BCAR1, PXN, CRKL, ZYX, SMAD2, PTK2B, PTK2, NCK1, ID2, RAPGEF1, PTPN12, CDH1, ABL1, PTPN11, LYN, LCK
Protein Size: 834

Molecular Weight: 93 kDa

Gene ID: 4739

NCBI Accession: NM_006403, NP_006394

UniProt: Q14511