APPBP2 antibody (Middle Region)

Catalog No. ABIN2784807

Product Details anti-APPBP2 Antibody

Target: APPBP2 (Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APPBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QASKACVVKR EFKKAEQLIK HAVYLARDHF GSKHPKYSDT LLDYGFYLLN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against APPBP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human APPBP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 585 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for APPBP2

Target: APPBP2 (Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))

Alternative Name: APPBP2 (APPBP2 Products)

Background: APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. APPBP2 has been found to be highly expressed in breast cancer.The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.
Alias Symbols: HS.84084, KIAA0228, PAT1
Protein Interaction Partner: WDR24, RASSF5, RNF34, CTC1, LONRF3, RNF128, SLC25A23, C1orf50, ZNF747, ARMCX5, CCNL1, LANCL2, UGGT2, ANKRD10, UBE2R2, FXYD7, LUC7L2, LUZP4, AK3, ERO1L, ST8SIA5, SNX5, RRS1, TCF25, SYNRG, FSTL1, TBL3, CORO2B, DHRS2, AIM2, KLF11, HIST1H2AK, NPRL3, WAS, TAF1
Protein Size: 585

Molecular Weight: 67 kDa

Gene ID: 10513

NCBI Accession: NM_006380, NP_006371

UniProt: Q92624