AP3M2 antibody (Middle Region)

Catalog No. ABIN2784846

Product Details anti-AP3M2 Antibody

Target: AP3M2 (Adaptor-Related Protein Complex 3, mu 2 Subunit (AP3M2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3M2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VVNTITGSTN VGDQLPTGQL SVVPWRRTGV KYTNNEAYFD VIEEIDAIID

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against AP3M2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AP3M2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 418 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-AP3M2 antibody (ABIN2784846)

Su, Ma, Li, Liu, Huang: "Pedicle screw fixation of the cervical spine: guidance by computed tomography." in: Clinical orthopaedics and related research, Vol. 462, pp. 99-104, (2007) (PubMed).

Target Details for AP3M2

Target: AP3M2 (Adaptor-Related Protein Complex 3, mu 2 Subunit (AP3M2))

Alternative Name: AP3M2 (AP3M2 Products)

Synonyms: wu:fc15g12 antibody, zgc:86670 antibody, AP47B antibody, CLA20 antibody, P47B antibody, 5830445E16Rik antibody, AP-3B antibody, adaptor related protein complex 3 mu 2 subunit antibody, AP-3 complex subunit mu-2 antibody, adaptor-related protein complex 3, mu 2 subunit antibody, adaptor related protein complex 3 mu 2 subunit S homeolog antibody, AP3M2 antibody, ap3m2 antibody, LOC582979 antibody, ap3m2.S antibody, Ap3m2 antibody

Background: AP3M2 is part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 3 (AP-3), which belongs to the adaptor complexes medium subunits family. The AP-3 complex plays a role in protein trafficking to lysosomes and specialized organelles.
Alias Symbols: AP47B, CLA20, P47B
Protein Interaction Partner: UBC, GRK5,
Protein Size: 418

Molecular Weight: 47 kDa

Gene ID: 10947

NCBI Accession: NM_006803, NP_006794

UniProt: P53677