GNB1 antibody (N-Term)

Catalog No. ABIN2785813

The Rabbit Polyclonal anti-GNB1 antibody has been validated for WB. It is suitable to detect GNB1 in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Guinea Pig, Horse and Rabbit. There is 1 publication available.

Quick Overview for GNB1 antibody (N-Term) (ABIN2785813)

Target: GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GNB1 Antibody

Binding Specificity: N-Term

Sequence: MSELDQLRQE AEQLKNQIRD ARKACADATL SQITNNIDPV GRIQMRTRRT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GNB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GNB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 340 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GNB1 antibody (ABIN2785813)

Ueda, Nagae, Kozawa, Morishita, Kimura, Nagase, Ohara, Yoshida, Asano: "Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42." in: The Journal of biological chemistry, Vol. 283, Issue 4, pp. 1946-53, (2008) (PubMed).

Target Details for GNB1

Target: GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))

Alternative Name: GNB1

Background: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. GNB1 is a bet
Alias Symbols: -
Protein Interaction Partner: UBC, SUMO2, SUMO3, MTOR, RICTOR, RPTOR, WDR26, GNG2, GNG8, GNG12, GNGT1, GNG7, GNG5, GNG3, TBXA2R, ADRB2, PAN2, SVIL, NOL11, CYFIP1, VCAM1, NCF2, MTNR1A, EPHA7, AFP, ESR1, Htt, GNAI3, GNAI2, GNAI1, GNA11, ATP6V1B1, AKT1, MRGPRX1, RADIL, RASD1, ATXN10, RAS
Protein Size: 340

Molecular Weight: 37 kDa

Gene ID: 2782

NCBI Accession: NM_002074, NP_002065

UniProt: P62873

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome