LGALS3BP antibody (Middle Region)

Catalog No. ABIN2785877

Product Details anti-LGALS3BP Antibody

Target: LGALS3BP (Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGALS3BP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NLSLYWSHEA LFQKKTLQAL EFHTVPFQLL ARYKGLNLTE DTYKPRIYTS

Predicted Reactivity: Cow: 83%, Dog: 83%, Human: 100%, Mouse: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against LGALS3BP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LGALS3BP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 585 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LGALS3BP

Target: LGALS3BP (Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP))

Alternative Name: LGALS3BP (LGALS3BP Products)

Synonyms: 90K antibody, BTBD17B antibody, MAC-2-BP antibody, TANGO10B antibody, Ppicap antibody, CyCAP antibody, MAC-2BP antibody, Tango10b antibody, lgals3bp antibody, zgc:136780 antibody, MAC2BP antibody, Mac-2 BP antibody, zgc:77059 antibody, galectin 3 binding protein antibody, lectin, galactoside-binding, soluble, 3 binding protein antibody, calcium activated nucleotidase 1 antibody, lectin, galactoside-binding, soluble, 3 binding protein a antibody, lectin, galactoside-binding, soluble, 3 binding protein b antibody, LGALS3BP antibody, Lgals3bp antibody, CANT1 antibody, lgals3bpa antibody, lgals3bpb antibody

Background: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: 90K, MAC-2-BP, BTBD17B
Protein Interaction Partner: GIGYF2, PRRC2C, CCT5, TUBB, CRTC2, RAVER1, TUBA1C, ENAH, CEP55, XRN2, CEP250, MAGED2, CCT8, CCT2, CCT4, CCT7, TUBGCP3, TUBB4B, TRAP1, BAG2, RPL23, IRS4, TUBA1A, MOGS, CCT3, TCP1, RPS4X, RPL38, HSPD1, HSP90AB1, HSP90AA1, HSPA8, HSPA5, HSPA1A, HNRNPU, CCT6A
Protein Size: 585

Molecular Weight: 63 kDa

Gene ID: 3959

NCBI Accession: NM_005567, NP_005558

UniProt: Q08380