PI4K2B antibody (N-Term)

Catalog No. ABIN2787116

Product Details anti-PI4K2B Antibody

Target: PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PI4K2B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EDPEFADIVL KAEQAIEIGV FPERISQGSS GSYFVKDSKR NIIGVFKPKS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Pi4k2b. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 469 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PI4K2B

Target: PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))

Alternative Name: Pi4k2b (PI4K2B Products)

Background: Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) Pi4k2b contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Pi4k2b contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
Alias Symbols: 2610042N09Rik, 4933409G22Rik
Protein Size: 469

Molecular Weight: 52 kDa

Gene ID: 67073

NCBI Accession: NM_025951, NP_080227

UniProt: Q8CBQ5

Pathways: Inositol Metabolic Process