MYL6 antibody (N-Term)

Catalog No. ABIN2787351

Product Details anti-MYL6 Antibody

Target: MYL6 (Myosin Light Chain 6, Alkali, Smooth Muscle and Non Muscle (MYL6))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Sheep, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYL6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: CDFTEDQTAE FKEAFQLFDR TGDGKILYSQ CGDVMRALGQ NPTNAEVLKV

Predicted Reactivity: Cow: 100%, Dog: 90%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against MYL6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYL6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 151 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYL6

Target: MYL6 (Myosin Light Chain 6, Alkali, Smooth Muscle and Non Muscle (MYL6))

Alternative Name: MYL6 (MYL6 Products)

Synonyms: ESMLC antibody, LC17 antibody, LC17-GI antibody, LC17-NM antibody, LC17A antibody, LC17B antibody, MLC-3 antibody, MLC1SM antibody, MLC3NM antibody, MLC3SM antibody, zgc:103624 antibody, MLC3nm antibody, Myln antibody, myosin light chain 6 antibody, myosin, light chain 6, alkali, smooth muscle and non-muscle antibody, myosin light chain 6 L homeolog antibody, myosin, light polypeptide 6, alkali, smooth muscle and non-muscle antibody, MYL6 antibody, Myl6 antibody, myl6 antibody, myl6.L antibody

Background: MYL6 contains 3 EF-hand domains. It is the regulatory light chain of myosin. MYL6 does not bind calcium. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: ESMLC, LC17-GI, LC17-NM, LC17A, LC17B, MLC1SM, MLC3NM, MLC3SM, LC17, MLC-3
Protein Interaction Partner: ADAMTS12, UBC, MDM2, SUZ12, MYL12A, MYH9, MYH14, GRIPAP1, UBD, GLP1R, PAN2, VCAM1, MLH1, ITGA4, FN1, TSGA10, ESR1, HSP90AB1, DES, ATP5B, MYL6B, LRRK2, CUL1, CDK2, ARRB1, ARRB2, SUMO2, SRRM2, USP45, USP46, USP18, MOB4, DNAJB9, NUDT21, EWSR1,
Protein Size: 151

Molecular Weight: 17 kDa

Gene ID: 4637

NCBI Accession: NM_079423, NP_524147

UniProt: P60660