TH1-Like antibody (N-Term)

Catalog No. ABIN2787403

Product Details anti-TH1-Like Antibody

Target: TH1-Like (TH1L)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TH1-Like antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GEGEDDAEVQ QECLHKFSTR DYIMEPSIFN TLKRYFQAGG SPENVIQLLS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against TH1L. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TH1L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 590 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TH1-Like

Target: TH1-Like (TH1L)

Alternative Name: TH1L (TH1L Products)

Synonyms: NELF-C antibody, NELF-D antibody, TH1 antibody, TH1L antibody, 2410003I03Rik antibody, C77797 antibody, Th1 antibody, Th1l antibody, th1l antibody, zgc:55482 antibody, negative elongation factor complex member C/D antibody, negative elongation factor complex member C/D, Th1l antibody, NELFCD antibody, Nelfcd antibody, nelfcd antibody

Background: The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini.
Alias Symbols: HSPC130, NELF-C, NELF-D, TH1, TH1L
Protein Interaction Partner: UBC, NELFA, PRMT5, ZNF638, UBE3A, POLR2C, SMAD4, ARAF, NELFB, NELFE, SUMO2, ATP1A1, CACNA1A, AR, FRMD5, ARPC4, HDAC11, ENDOV, SERF2, MTA1, AAMP, DNAJA1, TXK, GSTM4, EPRS, COPB2, RPS26, RPS14, RPS11, COX2, MCM7, EIF4G1, COX6C, COX6B1, COX5B, COX4I1, COX5A,
Protein Size: 590

Molecular Weight: 66 kDa

Gene ID: 51497

NCBI Accession: NM_198976, NP_945327

UniProt: Q8IXH7