General Transcription Factor IIB (GTF2B) (C-Term) antibody

Details for Product No. ABIN2787507, Supplier: Log in to see
Antigen
  • CG5193
  • Dmel\\CG5193
  • TFIIB
  • Tfiib
  • TfllB
  • dTFIIB
  • dTfIIB
  • dmTFIIB
  • gtf2b
  • tf2b
  • tfiib
  • XLTFIIB
  • TF2B
  • wu:fc44c11
  • zgc:66258
  • Transcription factor IIB
  • transcription initiation factor iib
  • transcription initiation factor IIB
  • transcription initiation factor IIB 2
  • Transcription initiation factor IIB
  • general transcription factor 2B S homeolog
  • general transcription factor 2B L homeolog
  • general transcription factor IIB
  • TfIIB
  • CNF01950
  • tfb
  • CC1G_14689
  • HacjB3_18813
  • HALXA_RS07110
  • HALXA_RS16310
  • tf2b
  • LOC100283348
  • gtf2b.S
  • gtf2b.L
  • GTF2B
  • gtf2b
  • Gtf2b
Epitope
C-Term
18
14
11
7
6
5
3
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
112
48
29
12
10
8
8
7
7
6
6
5
4
4
3
1
Host
Rabbit
76
39
Clonality
Polyclonal
Conjugate
Un-conjugated
7
7
6
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
84
43
13
13
10
9
6
6
3
3
3
2
2
1
1
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2B
Blocking Peptide Blocking peptide for this product available: ABIN977753
Sequence SVAAAAIYMA SQASAEKRTQ KEIGDIAGVA DVTIRQSYRL IYPRAPDLFP
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%
Characteristics This is a rabbit polyclonal antibody against GTF2B. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Antigen
Alternative Name GTF2B (GTF2B Antibody Abstract)
Background GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TF2B, TFIIB
Protein Interaction Partner: DRAP1, TNIP1, UBC, FBXO25, HNF4A, TCEA1, GTF2F2, GTF2F1, DEPDC7, SLC22A2, RELA, POLR2C, JAK3, HMGCL, SMURF1, THRA, TBP, POLR2E, SRA1, LSM4, LSM5, CIITA, NXF1, POU3F2, EP300, PSMA3, POLR2J, ESR1, UL48, NR1D2, NCOR1, TAF9, REST, tat, SAP25, MKX, CTDP1, POLR
Protein Size: 316
Molecular Weight 35 kDa
Gene ID 2959
NCBI Accession NM_001514, NP_001505
UniProt Q00403
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 316 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-General Transcription Factor IIB (GTF2B) (C-Term) antibody (ABIN2787507) WB Suggested Anti-GTF2B Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Elsby, ODonnell, Green, Sharrocks, Roberts: "Assembly of transcription factor IIB at a promoter in vivo requires contact with RNA polymerase II." in: EMBO reports, Vol. 7, Issue 9, pp. 898-903, 2006 (PubMed).

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