NMBR antibody (N-Term)

Catalog No. ABIN2787710

Product Details anti-NMBR Antibody

Target: NMBR (Neuromedin B Receptor (NMBR))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMBR antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PSKSLSNLSV TTGANESGSV PEGWERDFLP ASDGTTTELV IRCVIPSLYL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NMBR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NMBR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 390 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NMBR antibody (ABIN2787710)

Matusiak, Glover, Nathaniel, Matkowskyj, Yang, Benya: "Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 288, Issue 4, pp. G718-28, (2005) (PubMed).

Target Details for NMBR

Target: NMBR (Neuromedin B Receptor (NMBR))

Alternative Name: NMBR (NMBR Products)

Background: Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue.Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-100 AL589674.9 90178-90277 c 101-1308 M73482.1 99-1306 1309-1354 AL589674.9 77086-77131 c This locus represents an antisense transcript of the survivin locus. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-270 AF086186.1 11-280 271-869 AC087645.19 118062-118660 870-1098 L26245.1 740-968 1099-1286 BM839824.1 1-188 c
Alias Symbols: -
Protein Interaction Partner: NMB,
Protein Size: 390

Molecular Weight: 43 kDa

Gene ID: 4829

NCBI Accession: NM_002511, NP_002502

UniProt: P28336