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ARPC2 antibody (N-Term)

ARPC2 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787750
  • Target See all ARPC2 Antibodies
    ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))
    Binding Specificity
    • 15
    • 14
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 57
    • 12
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit
    Host
    • 52
    • 4
    • 1
    Rabbit
    Clonality
    • 51
    • 6
    Polyclonal
    Conjugate
    • 22
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARPC2 antibody is un-conjugated
    Application
    • 45
    • 23
    • 13
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    MVLNVYCCFF QISDIQTMKI NQTILKEFIL VGFSVYPHVQ TFLFVVFFCL
    Predicted Reactivity
    Cow: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ARPC2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ARPC2
    Top Product
    Discover our top product ARPC2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 300 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Al Ghouleh, Rodríguez, Pagano, Csányi: "Proteomic analysis identifies an NADPH oxidase 1 (Nox1)-mediated role for actin-related protein 2/3 complex subunit 2 (ARPC2) in promoting smooth muscle cell migration." in: International journal of molecular sciences, Vol. 14, Issue 10, pp. 20220-35, (2013) (PubMed).

  • Target
    ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))
    Alternative Name
    ARPC2 (ARPC2 Products)
    Synonyms
    arc34 antibody, p34-arc antibody, pnas-139 antibody, pro2446 antibody, Arpc2 antibody, Arc-p34 antibody, 2210023N03Rik antibody, 34kDa antibody, p34-Arc antibody, fk84a07 antibody, wu:fa22f07 antibody, wu:fk84a07 antibody, zgc:77769 antibody, ARC34 antibody, PNAS-139 antibody, actin related protein 2/3 complex subunit 2 antibody, actin related protein 2/3 complex, subunit 2, 34kDa antibody, actin related protein 2/3 complex, subunit 2 antibody, actin related protein 2/3 complex subunit 2 S homeolog antibody, ARPC2 antibody, arpc2 antibody, Arpc2 antibody, arpc2.S antibody
    Background
    ARPC2 is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of ARPC2, the p34 subunit, has yet to be determined. This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
    Alias Symbols: ARC34, PNAS-139, PRO2446, p34-Arc
    Protein Interaction Partner: SUMO2, UBC, ARPC5L, AARSD1, PUS1, NIF3L1, THG1L, NSUN2, SH3GLB1, LAP3, TPRKB, TNPO3, ANP32B, ACTR2, ACTR3, ARPC1B, ARPC3, ARPC4, ARPC5, TOM1L1, FUBP1, SUMO1, TPD52L2, SH3GL1, RPA2, RPA1, RANGAP1, PRKACB, PRKACA, PPP2R5D, PFDN5, PPP1R12A, MTR, METTL1, CALU
    Protein Size: 300
    Molecular Weight
    33 kDa
    Gene ID
    10109
    NCBI Accession
    NM_005731, NP_005722
    UniProt
    O15144
    Pathways
    RTK Signaling, Regulation of Actin Filament Polymerization
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