PUMA antibody (N-Term)
-
- Target See all PUMA (BBC3) Antibodies
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
-
Binding Specificity
- N-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PUMA antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- TTWVPCQICG PRERHGPRTP GGQLPGARRG PGPRRPAPLP ARPPGALGSV
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against BBC3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human BBC3
- Top Product
- Discover our top product BBC3 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 261 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Alternative Name
- BBC3 (BBC3 Products)
- Synonyms
- BBC3 antibody, Puma antibody, JFY-1 antibody, JFY1 antibody, PUMA antibody, PUMA/JFY1 antibody, BCL2 binding component 3 antibody, Bcl-2 binding component 3 antibody, BBC3 antibody, Bbc3 antibody, bbc3 antibody
- Background
-
BBC3 is an essential mediator of p53-dependent and p53-independent apoptosis.
Alias Symbols: FLJ42994, JFY1, PUMA, JFY-1
Protein Interaction Partner: BCL2L1, MCL1, ALB, BCL2L2, BCL2A1, BAX, BCL2, BNC1,
Protein Size: 261 - Molecular Weight
- 26 kDa
- Gene ID
- 27113
- NCBI Accession
- NM_001127240, NP_001120712
- UniProt
- Q96PG8
- Pathways
- p53 Signaling, Positive Regulation of Endopeptidase Activity
-