TNFSF4 antibody (Middle Region)

Catalog No. ABIN2787931

Product Details anti-TNFSF4 Antibody

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFSF4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QEVNISLHYQ KDEEPLFQLK KVRSVNSLMV ASLTYKDKVY LNVTTDNTSL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against TNFSF4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TNFSF4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 183 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TNFSF4

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Alternative Name: TNFSF4 (TNFSF4 Products)

Synonyms: TNFSF4 antibody, OX40L antibody, TNFRSF4 antibody, CD134L antibody, CD252 antibody, GP34 antibody, OX-40L antibody, OX4OL antibody, TXGP1 antibody, Ath-1 antibody, Ath1 antibody, Ox40l antibody, Txgp1l antibody, gp34 antibody, TNF superfamily member 4 antibody, tumor necrosis factor (ligand) superfamily, member 4 antibody, TNFSF4 antibody, Tnfsf4 antibody

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
Alias Symbols: CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1
Protein Interaction Partner: TRAF2, TNFRSF4,
Protein Size: 183

Molecular Weight: 21 kDa

Gene ID: 7292

NCBI Accession: NM_003326, NP_003317

UniProt: P23510

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints