SERPINB6 antibody (Middle Region)

Catalog No. ABIN2787990

Product Details anti-SERPINB6 Antibody

Target: SERPINB6 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 6 (SERPINB6))

Binding Specificity: Middle Region

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINB6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LVLVNAVYFR GNWDEQFDKE NTEERLFKVS KNEEKPVQMM FKQSTFKKTY

Predicted Reactivity: Cow: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SERPINB6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SERPINB6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 376 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SERPINB6

Target: SERPINB6 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 6 (SERPINB6))

Alternative Name: SERPINB6 (SERPINB6 Products)

Synonyms: Serpinb6a antibody, cap antibody, dfnb91 antibody, mstp057 antibody, pi6 antibody, pti antibody, serpinb8 antibody, spi3 antibody, 4930482L21Rik antibody, D330015H01Rik antibody, PI-6 antibody, Serpinb6 antibody, Spi3 antibody, ovalbumin antibody, CAP antibody, DFNB91 antibody, MSTP057 antibody, PI6 antibody, PTI antibody, SPI3 antibody, serpin family B member 6A antibody, serpin family B member 6 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 6a antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 6 antibody, Serpinb6a antibody, serpinb6 antibody, SERPINB6 antibody

Background: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: CAP, DKFZp686I04222, MGC111370, MSTP057, PI6, PTI, SPI3, DFNB91
Protein Interaction Partner: SUMO2, C16orf70, AHCY, CRK, UBC, F10, PLAU, F2, PROC, PLG, KLK2,
Protein Size: 376

Molecular Weight: 41 kDa

Gene ID: 5269

NCBI Accession: NM_004568, NP_004559

UniProt: P35237