CACNA2D4 antibody (C-Term)

Catalog No. ABIN2788223

Product Details anti-CACNA2D4 Antibody

Target: CACNA2D4 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 4 (CACNA2D4))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA2D4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAFLGTRAGL LRSSLFVGSE KVSDRKFLTP EDEASVFTLD RFPLWYRQAS

Predicted Reactivity: Cow: 85%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CACNA2D4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CACNA2D4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1137 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CACNA2D4

Target: CACNA2D4 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 4 (CACNA2D4))

Alternative Name: CACNA2D4 (CACNA2D4 Products)

Synonyms: cacna2d4 antibody, cacna2d3b antibody, si:ch211-87p6.2 antibody, RCD4 antibody, 5730412N02Rik antibody, BE686333 antibody, RGD1562038 antibody, calcium voltage-gated channel auxiliary subunit alpha2delta 4 antibody, calcium channel, voltage-dependent, alpha 2/delta subunit 4a antibody, calcium channel, voltage-dependent, alpha 2/delta subunit 4b antibody, uncharacterized LOC100630648 antibody, calcium channel, voltage-dependent, alpha 2/delta subunit 4 antibody, CACNA2D4 antibody, cacna2d4a antibody, cacna2d4b antibody, cacna2d4 antibody, LOC100630648 antibody, Cacna2d4 antibody

Background: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Alias Symbols: RCD4
Protein Size: 1137

Molecular Weight: 128 kDa

Gene ID: 93589

NCBI Accession: NM_172364, NP_758952

UniProt: Q7Z3S7