Lcor antibody (Middle Region)

Catalog No. ABIN2788237

Product Details anti-Lcor Antibody

Target: Lcor (Ligand Dependent Nuclear Receptor Corepressor (Lcor))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lcor antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NLSRMKFRGN GALSNISDLP FLAENSAFPK MALQAKQDGK KDVSHSSPVD

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LCOR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LCOR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 433 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Lcor

Target: Lcor (Ligand Dependent Nuclear Receptor Corepressor (Lcor))

Alternative Name: LCOR (Lcor Products)

Synonyms: 3110023F06Rik antibody, A630025C20Rik antibody, Mlr2 antibody, mKIAA1795 antibody, MLR2 antibody, RGD1311704 antibody, wu:fd05a07 antibody, zgc:158268 antibody, mlr2 antibody, ligand dependent nuclear receptor corepressor antibody, ligand dependent nuclear receptor corepressor S homeolog antibody, Lcor antibody, LCOR antibody, lcor.S antibody, lcor antibody

Background: LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).
Alias Symbols: FLJ38026, KIAA1795, MLR2, RP11-175O19.1
Protein Interaction Partner: TRAF1, GOLGA2, CTBP2, CTBP1, AR, KLF6, HDAC6, HDAC4, VDR, HDAC1, ESR1, HDAC3,
Protein Size: 433

Molecular Weight: 47 kDa

Gene ID: 84458

NCBI Accession: NM_032440, NP_115816

UniProt: Q96JN0