COL8a2 antibody (Middle Region)

Catalog No. ABIN2788308

Product Details anti-COL8a2 Antibody

Target: COL8a2 (COL8A2) (Collagen, Type VIII, alpha 2 (COL8A2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio), Goat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL8a2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AAGLPGPQGP SGAKGEPGTR GPPGLIGPTG YGMPGLPGPK GDRGPAGVPG

Predicted Reactivity: Cow: 93%, Dog: 92%, Goat: 85%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 92%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against COL8A2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COL8A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 703 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COL8a2

Target: COL8a2 (COL8A2) (Collagen, Type VIII, alpha 2 (COL8A2))

Alternative Name: COL8A2 (COL8A2 Products)

Synonyms: FECD antibody, FECD1 antibody, PPCD antibody, PPCD2 antibody, AI429819 antibody, collagen type VIII alpha 2 chain antibody, collagen, type VIII, alpha 2 antibody, COL8A2 antibody, Col8a2 antibody

Background: COL8A2 is the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this COL8A2 gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2
Alias Symbols: FECD, FECD1, FLJ00201, MGC116970, MGC116972, PPCD, PPCD2
Protein Interaction Partner: SGTA, COL8A1,
Protein Size: 703

Molecular Weight: 67 kDa

Gene ID: 1296

NCBI Accession: NM_005202, NP_005193

UniProt: P25067