CAMK2B antibody (C-Term)

Catalog No. ABIN2788742

Product Details anti-CAMK2B Antibody

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMK2B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NPHVHVIGED AACIAYIRLT QYIDGQGRPR TSQSEETRVW HRRDGKWQNV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CAMK2B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CAMK2B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 542 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAMK2B

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Alternative Name: CAMK2B (CAMK2B Products)

Synonyms: CAM2 antibody, CAMK2 antibody, CAMKB antibody, Camk2d antibody, Ck2b antibody, camk2 antibody, camk2b antibody, cam2 antibody, camkb antibody, CAMK2B antibody, calcium/calmodulin dependent protein kinase II beta antibody, calcium/calmodulin-dependent protein kinase II, beta antibody, calcium/calmodulin-dependent protein kinase II beta antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II beta L homeolog antibody, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta antibody, CAMK2B antibody, Camk2b antibody, camk2a.S antibody, camk2b.L antibody

Background: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.
Alias Symbols: CAM2, CAMK2, CAMKB, MGC29528
Protein Interaction Partner: KRTAP10-11, KRTAP19-7, KRTAP19-5, FAM171A2, MGAT5B, CCM2L, TTC5, AP5B1, MRPL11, SEMA4G, SPRYD7, MED18, POP5, RBFOX2, ACOT7, RBPMS, MORF4L1, MAD2L2, RPL11, RAP2B, PHKB, CAMK2B, MVP, SMYD3, UBC, ATXN1, HSP90AA1, Rad23a, THRB, RXRG, YWHAB, CAMK2N2, CAMK2D, A
Protein Size: 542

Molecular Weight: 60 kDa

Gene ID: 816

NCBI Accession: NM_172078, NP_742075

UniProt: Q53H78

Pathways: WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity