PFKP antibody (C-Term)
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- Target See all PFKP Antibodies
- PFKP (phosphofructokinase, Platelet (PFKP))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PFKP antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EWITAKLKEA RGRGKKFTTD DSICVLGISK RNVIFQPVAE LKKQTDFEHR
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PFKP. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PFKP Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 784 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PFKP (phosphofructokinase, Platelet (PFKP))
- Alternative Name
- PFKP (PFKP Products)
- Synonyms
- pfk antibody, pfk-c antibody, pfkf antibody, PFKP antibody, PFK-C antibody, PFKF antibody, 1200015H23Rik antibody, 9330125N24Rik antibody, PFKM antibody, phosphofructokinase, platelet antibody, phosphofructokinase, platelet S homeolog antibody, ATP-dependent 6-phosphofructokinase, platelet type antibody, pfkp antibody, PFKP antibody, pfkp.S antibody, LOC100549777 antibody, Pfkp antibody
- Background
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The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM, MIM 610681) and liver (PFKL, MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.
Alias Symbols: FLJ40226, PFK-C, PFKF
Protein Interaction Partner: UBC, SUMO2, EGFR, rev, VAT1, TUBB4B, PPIB, PFKM, PCBP1, EEF1A1, CRYZ, HIPK4, FBXO6, MAPK4, HDAC6, SOX2, ILK, CD81, WNK1, AGO2, ITGA4, FN1, TMPO, PFKL, EPRS, COPS5, CUL3, ACD, PARD3, TINF2, FBXO25, POT1, TERF1, SIRT7, WIPI2, GBAS, DMWD, DYNLL1, MCC,
Protein Size: 784 - Molecular Weight
- 85 kDa
- Gene ID
- 5214
- NCBI Accession
- NM_002627, NP_002618
- UniProt
- Q01813
- Pathways
- Warburg Effect
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