BAAT1 antibody (C-Term)

Catalog No. ABIN2789238

Product Details anti-BAAT1 Antibody

Target: BAAT1 (C7orf27) (Chromosome 7 Open Reading Frame 27 (C7orf27))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAAT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FDCDRPVAQK SCDLLLFLRD KIASYSSLRE ARGSPNTASA EATLPRWRAG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against BRAT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human BRAT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 821 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BAAT1

Target: BAAT1 (C7orf27) (Chromosome 7 Open Reading Frame 27 (C7orf27))

Alternative Name: BRAT1 (C7orf27 Products)

Synonyms: C7orf27 antibody, BAAT1 antibody, RMFSL antibody, AA881470 antibody, Baat1 antibody, baat1 antibody, zgc:136845 antibody, BRCA1 associated ATM activator 1 antibody, BRCA1-associated ATM activator 1 antibody, BRAT1 antibody, Brat1 antibody, brat1 antibody

Background: The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM.
Alias Symbols: MGC22916, BAAT1, C7orf27
Protein Interaction Partner: UBC, BRCA1, USP48, VCP, ATM, SUMO2,
Protein Size: 821

Molecular Weight: 87 kDa

Gene ID: 221927

NCBI Accession: NM_152743, NP_689956

UniProt: Q6PJG6