DACT1 antibody (N-Term)

Catalog No. ABIN2789247

Product Details anti-DACT1 Antibody

Target: DACT1 (Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DACT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LRLDVEKTSE EHLETDSRPS SGFYELSDGA SGSLSNSSNS VFSECLSSCH

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against DACT1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 836 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DACT1

Target: DACT1 (Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1))

Alternative Name: DACT1 (DACT1 Products)

Synonyms: XDpr antibody, dpr1 antibody, frodo antibody, hdpr1 antibody, Dapper antibody, thyex3 antibody, dapper1 antibody, MGC89695 antibody, frd1 antibody, frodo1 antibody, 4921528D17Rik antibody, AI115603 antibody, DAPPER antibody, DAPPER1 antibody, FRODO antibody, Frd1 antibody, Frodo1 antibody, MDpr1 antibody, MTNG3 antibody, THYEX3 antibody, DPR1 antibody, HDPR1 antibody, DACT1 antibody, RGD1564008 antibody, XDpr1a antibody, dact1 antibody, dpr antibody, XDpr1b antibody, dishevelled-binding antagonist of beta-catenin 1 antibody, dishevelled binding antagonist of beta catenin 1 antibody, dishevelled-binding antagonist of beta-catenin 1 L homeolog antibody, dishevelled-binding antagonist of beta-catenin 1 S homeolog antibody, dact1 antibody, Dact1 antibody, DACT1 antibody, dact1.L antibody, dact1.S antibody

Background: DACT1 positively regulates DVL2-mediated signaling pathways during development. It binds to DVL2 and impedes the degradation of CTNNB1/beta-catenin, thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway.
Alias Symbols: DAPPER, DAPPER1, DPR1, FRODO, HDPR1, THYEX3
Protein Interaction Partner: BECN1, PIK3C3, ATG14, CBX6, PPP1CC, Dact1, Dact3, C7orf25, TK1, SH3GL2, CSNK2B, LEF1, HDAC1,
Protein Size: 836

Molecular Weight: 92 kDa

Gene ID: 51339

NCBI Accession: NM_016651, NP_057735

UniProt: Q9NYF0

Pathways: Positive Regulation of fat Cell Differentiation