STAM antibody (N-Term)

Catalog No. ABIN2789368

Product Details anti-STAM Antibody

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAM antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EQAKASPALV AKDPGTVANK KEEEDLAKAI ELSLKEQRQQ STTLSTLYPS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against STAM. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 540 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STAM

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Alternative Name: STAM (STAM Products)

Synonyms: STAM-1 antibody, STAM1 antibody, wu:fv75b10 antibody, zgc:55725 antibody, RGD1564499 antibody, signal transducing adaptor molecule antibody, signal transducing adapter molecule 1 antibody, Signal transducing adapter molecule 1 antibody, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 antibody, STAM antibody, CpipJ_CPIJ003516 antibody, Tsp_03939 antibody, stam-1 antibody, Stam antibody, stam antibody

Background: This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.
Alias Symbols: DKFZp686J2352, STAM1, STAM-1
Protein Interaction Partner: DTX3L, HGS, UBC, CLTC, Chmp3, UBE4B, STAMBP, YWHAB, SNTA1, Mbp, MED28, PPP1CA, PPP1CC, UBQLN4, UBQLN2, PRDX5, STMN2, CPLX1, AHCYL1, SSSCA1, STUB1, USP34, ZRANB2, ZPR1, PIR, TPM2, SULT1A1, S100A11, PPM1G, IGBP1, SERPINH1, TBCK, UNK, THADA, TRIM54, USP15, R
Protein Size: 540

Molecular Weight: 59 kDa

Gene ID: 8027

NCBI Accession: NM_003473, NP_003464

UniProt: Q92783

Pathways: EGFR Signaling Pathway, EGFR Downregulation