IKKi/IKKe antibody (N-Term)

Catalog No. ABIN2789403

Product Details anti-IKKi/IKKe Antibody

Target: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Binding Specificity: N-Term

Reactivity: Human, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKKi/IKKe antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AGAIAGAQRR ENGPLEWSYT LPITCQLSLG LQSQLVPILA NILEVEQAKC

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against IKBKE. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 631 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IKKi/IKKe

Target: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Alternative Name: IKBKE (IKBKE Products)

Synonyms: zgc:100844 antibody, IKBKE antibody, MGC130907 antibody, IKK-E antibody, IKK-i antibody, IKKE antibody, IKKI antibody, AW558201 antibody, IKKepsilon antibody, Ikki antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon antibody, inhibitor of nuclear factor kappa B kinase subunit epsilon antibody, inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog antibody, inhibitor of kappaB kinase epsilon antibody, IKBKE antibody, ikbke antibody, ikbke.L antibody, Ikbke antibody

Background: IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30 % of breast carcinomas and breast cancer cell lines.
Alias Symbols: IKK-i, IKKE, IKKI, KIAA0151, MGC125294, MGC125295, MGC125297, IKK-E
Protein Interaction Partner: CD209, TRIM6, UBC, TRAF3, NMRAL1, DDX58, MAFB, MYD88, IKBKB, HSP90AA1, DDX3X, CYLD, BIRC3, BIRC2, AZI2, TRAF3IP2, TANK, TBKBP1, IKBKE, IKBKG, TRAF2, RNF11, NFKBIA, TOPORS, SUMO1, SUMO2, SUMO3, TRIM27, PML, MAVS, TBK1, MBP, TNIP1, TAX1BP1, TNFAIP3, IRF3, C
Protein Size: 631

Molecular Weight: 69 kDa

Gene ID: 9641

NCBI Accession: NM_001193321, NP_001180250

UniProt: Q3B754

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades