CD94 antibody (Middle Region)

Catalog No. ABIN2789440

Product Details anti-CD94 Antibody

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD94 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CQEKWVGYRC NCYFISSEQK TWNESRHLCA SQKSSLLQLQ NTDELDFMSS

Predicted Reactivity: Human: 100%, Mouse: 79%

Characteristics: This is a rabbit polyclonal antibody against KLRD1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 179 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD94

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Alternative Name: KLRD1 (KLRD1 Products)

Synonyms: CD94 antibody, CD94-B antibody, Cd94 antibody, killer cell lectin like receptor D1 antibody, killer cell lectin-like receptor subfamily D, member 1 antibody, killer cell lectin-like receptor, subfamily D, member 1 antibody, KLRD1 antibody, Klrd1 antibody

Background: Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: CD94
Protein Interaction Partner: KLRD1, KLRC3, KLRC2, KLRC1, HLA-E, HLA-G, HLA-B,
Protein Size: 179

Molecular Weight: 20 kDa

Gene ID: 3824

NCBI Accession: NM_002262, NP_002253

UniProt: Q13241