TUBB3 antibody (C-Term)

Catalog No. ABIN2789623

Product Details anti-TUBB3 Antibody

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBB3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LHWYTGEGMD EMEFTEAESN MNDLVSEYQQ YQDATAEEEG EMYEDDEEES

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TUBB3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 450 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TUBB3 antibody (ABIN2789623)

Xavier, Ludwig, Nagai, de Almeida, Watanabe, Hirata, Rosenstock, Papes, Malnic, Glezer: "CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium." in: Scientific reports, Vol. 6, pp. 25507, (2016) (PubMed).

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: TUBB3 (TUBB3 Products)

Synonyms: CDCBM antibody, CFEOM3A antibody, TUBB4 antibody, beta-4 antibody, TUBB3 antibody, 3200002H15Rik antibody, M(beta)3 antibody, M(beta)6 antibody, tubb3 antibody, tubulin beta 3 class III antibody, tubulin, beta 3 class III antibody, tubulin beta 3 class III L homeolog antibody, beta-tubulin 3 antibody, tubulin beta-3 chain antibody, beta tubulin 3 antibody, TUBB3 antibody, Tubb3 antibody, tubb3 antibody, tubb3.L antibody, LOC100581245 antibody, tub3 antibody

Background: This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
Alias Symbols: CFEOM3A, MC1R, TUBB4, beta-4, CDCBM
Protein Interaction Partner: UBC, HAUS2, CEP250, MAPT, EMD, EML1, ASB18, ASB8, ASB17, ASB4, rev, PAPSS1, VCL, RARS, MSN, STK26, CAPZB, CAPZA1, ACAT2, FBXO6, EGFR, CD81, HDAC6, SOX2, NPM1, IQCB1, TPTE, FAM86B2, METTL23, CAMKMT, VCPKMT, METTL22, METTL21B, PEX14, GZMK, TUBA1C, MDN1, TUB
Protein Size: 450

Molecular Weight: 50 kDa

Gene ID: 10381

NCBI Accession: NM_006086, NP_006077

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase