GGA2 antibody (N-Term)

Catalog No. ABIN2789726

Product Details anti-GGA2 Antibody

Target: GGA2 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MLKKQGIIKQ DPKLPVDKIL PPPSPWPKSS IFDADEEKSK LLTRLLKSNH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GGA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GGA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 613 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GGA2

Target: GGA2 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2))

Alternative Name: GGA2 (GGA2 Products)

Synonyms: 1200007E24Rik antibody, mKIAA1080 antibody, VEAR antibody, golgi associated, gamma adaptin ear containing, ARF binding protein 2 antibody, Gga2 antibody, GGA2 antibody

Background: This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
Alias Symbols: VEAR
Protein Interaction Partner: RNF11, CA8, ARF1, UBC, UBI4, SYNRG, RABEP1, ATXN1, MAP1A, HTT, VCP, APP, CPLX1, IGF2R, SORT1, GGA1, STAB1, GGA3, TOLLIP, BACE1, CLTC, CCDC91, VPS18, RABGEF1, AFTPH, SPG21, GGA2, CLINT1, LRP3, SORL1, TRIM23, PIN1, M6PR, ARF3, HGS, BACE2, RAB5A, NECAP2,
Protein Size: 613

Molecular Weight: 67 kDa

Gene ID: 23062

NCBI Accession: NM_015044, NP_055859

UniProt: Q9UJY4