CACNA2D2 antibody (C-Term)

Catalog No. ABIN2789908

Product Details anti-CACNA2D2 Antibody

Target: CACNA2D2 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA2D2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NCSRLFHAQR LTNTNLLFVV AEKPLCSQCE AGRLLQKETH SDGPEQCELV

Predicted Reactivity: Cow: 76%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 81%, Rat: 81%

Characteristics: This is a rabbit polyclonal antibody against CACNA2D2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CACNA2D2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1143 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CACNA2D2

Target: CACNA2D2 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2))

Alternative Name: CACNA2D2 (CACNA2D2 Products)

Synonyms: CACNA2D antibody, LUAC11.1 antibody, Cacna2d antibody, a2d2 antibody, du antibody, mKIAA0558 antibody, td antibody, torpid antibody, calcium voltage-gated channel auxiliary subunit alpha2delta 2 antibody, calcium channel, voltage-dependent, alpha 2/delta subunit 2 antibody, CACNA2D2 antibody, Cacna2d2 antibody

Background: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
Alias Symbols: CACNA2D, KIAA0558, LUAC11.1
Protein Interaction Partner: UBC,
Protein Size: 1143

Molecular Weight: 129 kDa

Gene ID: 9254

NCBI Accession: NM_006030, NP_006021

Pathways: Skeletal Muscle Fiber Development