CTDP1 antibody (C-Term)
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- Target See all CTDP1 Antibodies
- CTDP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Phosphatase, Subunit 1 (CTDP1))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Dog, Horse, Pig, Rabbit, Rat, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CTDP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AHAPDKEPEL GGQEEGERDG LCGLGNGCAD RKEAETESQN SELSGVTAGE
- Predicted Reactivity
- Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Characteristics
- This is a rabbit polyclonal antibody against CTDP1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTDP1
- Top Product
- Discover our top product CTDP1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 867 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CTDP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Phosphatase, Subunit 1 (CTDP1))
- Alternative Name
- CTDP1 (CTDP1 Products)
- Synonyms
- CTDP1 antibody, CCFDN antibody, FCP1 antibody, 4930563P03Rik antibody, AW553592 antibody, CTD phosphatase subunit 1 antibody, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 antibody, RNA polymerase II subunit A C-terminal domain phosphatase antibody, CTD phosphatase Fcp1 antibody, Ctdp1 antibody, CTDP1 antibody, ctdp1 antibody, ANI_1_2668024 antibody, AOR_1_1228154 antibody, CpipJ_CPIJ004583 antibody, PTRG_11566 antibody, SJAG_01286 antibody, MCYG_05528 antibody, VDBG_09811 antibody
- Background
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This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: CCFDN, FCP1
Protein Interaction Partner: UBC, CDK9, UPP1, PPP2CA, PPP1CA, POLR2A, POLR2C, GRK5, ELP2, ELP3, SUMO2, PRKDC, CDK8, CDK7, INTS8, MED15, MED4, INTS6, INTS1, INTS7, MED16, MED6, MED24, MED7, MED26, MED17, MED23, MED14, MED1, MED8, MED25, INTS3, POLR2J, ERH, POLR2B, STK38, PRMT5, HIST1H
Protein Size: 867 - Molecular Weight
- 93 kDa
- Gene ID
- 9150
- NCBI Accession
- NM_048368, NP_430255
- UniProt
- Q9Y5B0
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