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CTDP1 antibody (C-Term)

CTDP1 Reactivity: Human, Mouse, Dog, Horse, Pig, Rabbit, Rat, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2790245
  • Target See all CTDP1 Antibodies
    CTDP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Phosphatase, Subunit 1 (CTDP1))
    Binding Specificity
    • 12
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Dog, Horse, Pig, Rabbit, Rat, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 32
    • 3
    Rabbit
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTDP1 antibody is un-conjugated
    Application
    • 24
    • 17
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    AHAPDKEPEL GGQEEGERDG LCGLGNGCAD RKEAETESQN SELSGVTAGE
    Predicted Reactivity
    Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against CTDP1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTDP1
    Top Product
    Discover our top product CTDP1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 867 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CTDP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Phosphatase, Subunit 1 (CTDP1))
    Alternative Name
    CTDP1 (CTDP1 Products)
    Synonyms
    CTDP1 antibody, CCFDN antibody, FCP1 antibody, 4930563P03Rik antibody, AW553592 antibody, CTD phosphatase subunit 1 antibody, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 antibody, RNA polymerase II subunit A C-terminal domain phosphatase antibody, CTD phosphatase Fcp1 antibody, Ctdp1 antibody, CTDP1 antibody, ctdp1 antibody, ANI_1_2668024 antibody, AOR_1_1228154 antibody, CpipJ_CPIJ004583 antibody, PTRG_11566 antibody, SJAG_01286 antibody, MCYG_05528 antibody, VDBG_09811 antibody
    Background
    This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: CCFDN, FCP1
    Protein Interaction Partner: UBC, CDK9, UPP1, PPP2CA, PPP1CA, POLR2A, POLR2C, GRK5, ELP2, ELP3, SUMO2, PRKDC, CDK8, CDK7, INTS8, MED15, MED4, INTS6, INTS1, INTS7, MED16, MED6, MED24, MED7, MED26, MED17, MED23, MED14, MED1, MED8, MED25, INTS3, POLR2J, ERH, POLR2B, STK38, PRMT5, HIST1H
    Protein Size: 867
    Molecular Weight
    93 kDa
    Gene ID
    9150
    NCBI Accession
    NM_048368, NP_430255
    UniProt
    Q9Y5B0
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