ARHGAP22 antibody (C-Term)

Catalog No. ABIN2790394

Product Details anti-ARHGAP22 Antibody

Target: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP22 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AGAGASNSEP SEPDSPTREH ARRSEALQGL VTELRAELCR QRTEYERSVK

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ARHGAP22. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ARHGAP22

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 698 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARHGAP22

Target: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Alternative Name: ARHGAP22 (ARHGAP22 Products)

Synonyms: si:ch211-223a10.2 antibody, RhoGAP2 antibody, RhoGap22 antibody, B230341L19Rik antibody, RHOGAP2 antibody, p68RacGAP antibody, Rho GTPase activating protein 22 antibody, rho GTPase activating protein 22 antibody, ARHGAP22 antibody, arhgap22 antibody, CC1G_06014 antibody, Arhgap22 antibody

Background: This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: RhoGAP2
Protein Interaction Partner: CCNDBP1, CACNA1A,
Protein Size: 698

Molecular Weight: 77 kDa

Gene ID: 58504

NCBI Accession: NM_021226, NP_067049

UniProt: Q7Z5H3