IDH3B antibody (N-Term)

Catalog No. ABIN2790476

Product Details anti-IDH3B Antibody

Target: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDH3B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RIAKFAFDYA TKKGRGKVTA VHKANIMKLG DGLFLQCCEE VAELYPKIKF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against IDH3B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IDH3B

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IDH3B

Target: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Alternative Name: IDH3B (IDH3B Products)

Synonyms: H-IDHB antibody, RP46 antibody, C78231 antibody, zgc:86647 antibody, MGC79028 antibody, IDH1 antibody, IDH3 antibody, isocitrate dehydrogenase 3 (NAD(+)) beta antibody, isocitrate dehydrogenase 3 (NAD+) beta antibody, isocitrate dehydrogenase 3 (NAD+) beta S homeolog antibody, IDH3B antibody, Idh3B antibody, Idh3b antibody, idh3b antibody, idh3b.S antibody

Background: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Protein Interaction Partner: TP53, SUMO2, ADRB2, MMS19, ATXN2, UBC, EBNA-LP, MAPK6, MYC, RAB35, PRMT1, IDH3A, IDH3G,
Protein Size: 233

Molecular Weight: 25 kDa

Gene ID: 3420