ATPBD3 antibody (C-Term)

Catalog No. ABIN2790748

Product Details anti-ATPBD3 Antibody

Target: ATPBD3 (CTU1) (Cytosolic Thiouridylase Subunit 1 Homolog (CTU1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATPBD3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ALASRALCQA CALLDGLNRG RPRLAIGKGR RGLDEEATPG TPGDPARPPA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CTU1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTU1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 348 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATPBD3

Target: ATPBD3 (CTU1) (Cytosolic Thiouridylase Subunit 1 Homolog (CTU1))

Alternative Name: CTU1 (CTU1 Products)

Synonyms: ATPBD3 antibody, NCS6 antibody, atpbd3 antibody, ncs6 antibody, Atpbd3 antibody, RGD1308740 antibody, BC005752 antibody, zgc:55395 antibody, cytosolic thiouridylase subunit 1 antibody, cytosolic thiouridylase subunit 1 L homeolog antibody, cytosolic thiouridylase subunit 1 homolog (S. pombe) antibody, CTU1 antibody, ctu1.L antibody, Ctu1 antibody, ctu1 antibody

Background: CTU1 plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). CTU1 directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Alias Symbols: ATPBD3, NCS6
Protein Interaction Partner: FAM96B, CIAO1, MMS19, CTU2, URM1, HSPA4,
Protein Size: 348

Molecular Weight: 38 kDa

Gene ID: 90353

NCBI Accession: NM_145232, NP_660275

UniProt: Q7Z7A3