PPM1L antibody (Middle Region)

Catalog No. ABIN2790848

Product Details anti-PPM1L Antibody

Target: PPM1L (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Horse, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1L antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SRLPEALKQH LQDYEKDKEN SVLSYQTILE QQILSIDREM LEKLTVSYDE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PPM1L. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PPM1L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 360 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPM1L

Target: PPM1L (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L))

Alternative Name: PPM1L (PPM1L Products)

Synonyms: 3222401G13 antibody, 5930404J21Rik antibody, AI481720 antibody, AW045850 antibody, PP2C antibody, PP2Cepsilon antibody, Pp2ce antibody, Ppp2ce antibody, mKIAA4175 antibody, PP2C-epsilon antibody, PP2CE antibody, PPM1-LIKE antibody, ppm1l antibody, zgc:153235 antibody, zgc:154091 antibody, protein phosphatase 1 (formerly 2C)-like antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1L antibody, protein phosphatase, Mg2+/Mn2+ dependent 1L antibody, protein phosphatase, Mg2+/Mn2+ dependent 1L L homeolog antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Lb antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1La antibody, Ppm1l antibody, PPM1L antibody, ppm1l.L antibody, ppm1lb antibody, ppm1la antibody

Background: PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. PP2Cs regulate stress-activated protein kinase signaling cascades that respond to extracellular stimuli.
Alias Symbols: MGC132545, MGC132547, PP2C-epsilon, PP2CE, PPM1-LIKE
Protein Interaction Partner: MAP3K7,
Protein Size: 360

Molecular Weight: 40 kDa

Gene ID: 151742

NCBI Accession: NM_139245, NP_640338

UniProt: Q5SGD2