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NSMCE4A antibody (C-Term)

NSMCE4A Reactivity: Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2791705
  • Target See all NSMCE4A Antibodies
    NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))
    Binding Specificity
    • 8
    • 8
    • 7
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    This NSMCE4A antibody is un-conjugated
    Application
    • 18
    • 12
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    PVIQEERAMP AQLRRMEESH QEATEKEVER ILGLLQTYFR EDPDTPMSFF
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against NSMCE4A. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSMCE4A
    Top Product
    Discover our top product NSMCE4A Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))
    Alternative Name
    NSMCE4A (NSMCE4A Products)
    Synonyms
    2410003A14Rik antibody, RGD1309025 antibody, C10orf86 antibody, NS4EA antibody, NSE4A antibody, NSE4 homolog A, SMC5-SMC6 complex component antibody, Nsmce4a antibody, NSMCE4A antibody
    Background
    NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
    Alias Symbols: C10orf86, NS4EA, NSE4A
    Protein Interaction Partner: UBC, HECW2, SRPK2, SRPK1, MAGED4B, NDNL2, MAGEC2, MAGEH1, MAGED2, NDN, MAGEB1, MAGEA1, NSMCE1, SMC6,
    Protein Size: 385
    Molecular Weight
    44 kDa
    Gene ID
    54780
    NCBI Accession
    NM_017615, NP_060085
    UniProt
    Q9NXX6
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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