PPIA antibody (Middle Region)

Catalog No. ABIN2791868

Product Details anti-PPIA Antibody

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Horse, Guinea Pig, Sheep, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NGTGGKSIYG EKFEDENFIL KHTGPGILSM ANAGPNTNGS QFFICTAKTE

Predicted Reactivity: Cow: 92%, Dog: 92%, Goat: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 83%, Rat: 92%, Sheep: 92%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against PPIA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PPIA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPIA

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Alternative Name: PPIA (PPIA Products)

Synonyms: Cyp1 antibody, PPIA-2 antibody, fa93g09 antibody, ppia antibody, wu:fa93g09 antibody, wu:fb05e11 antibody, wu:fb13h02 antibody, wu:fb15a05 antibody, CYPA antibody, CypA antibody, Cypa antibody, CYPH antibody, CYCA antibody, CyP-A antibody, MGC75715 antibody, 2700098C05 antibody, Cphn antibody, CyP-18 antibody, MT-ND1 antibody, MTND1 antibody, NADH1 antibody, ND1 antibody, cypA antibody, PPIase A antibody, ppial antibody, wu:fj18g05 antibody, zgc:73102 antibody, zgc:86688 antibody, peptidylprolyl isomerase A antibody, peptidylprolyl isomerase Aa (cyclophilin A) antibody, peptidylprolyl isomerase A (cyclophilin A) L homeolog antibody, cyclophilin A antibody, cyclophilin a antibody, peptidylprolyl isomerase A (cyclophilin A) antibody, peptidylprolyl isomerase Ab (cyclophilin A) antibody, PPIA antibody, ppiaa antibody, ppia.L antibody, Cypa antibody, CNB01230 antibody, CNB01290 antibody, Tc00.1047053506925.300 antibody, Tb11.03.0250 antibody, CYPA antibody, Ppia antibody, ppia antibody, ppiab antibody

Background: PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.
Protein Interaction Partner: LNX1, HUWE1, UBC, TCF4, FUS, gag, MDM2, RPL23A, SRPK2, SRPK1, ESR1, UBD, TERT, RAD52, VCAM1, ITGA4, FN1, HCVgp1, LIG4, PAXIP1, RB1, APP, CPLX1, SNX3, TAGLN2, SOD1, RPA2, RAD23B, PTMA, IGBP1, ENO1, AKT1, USP4, CDK2, COPS5, CUL1, CUL3, CUL4B, NEDD8, CD99, C
Protein Size: 164

Molecular Weight: 18 kDa

Gene ID: 5478

UniProt: P62937