PSMD5 antibody (C-Term)

Catalog No. ABIN2791885

Product Details anti-PSMD5 Antibody

Target: PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FEMIESQDPT MIGVAVDTVG ILGSNVEGKQ VLQKTGTRFE RLLMRIGHQS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PSMD5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PSMD5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSMD5

Target: PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))

Alternative Name: PSMD5 (PSMD5 Products)

Synonyms: S5B antibody, 1500032A03Rik antibody, AW475925 antibody, S5b antibody, W91691 antibody, mKIAA0072 antibody, proteasome 26S subunit, non-ATPase 5 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 antibody, PSMD5 antibody, Psmd5 antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.
Alias Symbols: S5B
Protein Interaction Partner: UBC, TFCP2, PSMC2, PSMC1, PPME1, GMPS, PNP, PARK2, RNF11, BAG3, FN1, MACF1, PSMD13, PSMD7, PSMD2, PSMD1, PSMB5, PSMB4, PSMB2, PSMB1, PSMA7, PSMA6, PSMA4, PSMA2, PSMA1, APP, PSMD4, COPS2, RAD23A, ELAVL1, PMS2, RPN7, RPN2, RPT1, RPT2,
Protein Size: 504

Molecular Weight: 55 kDa

Gene ID: 5711

NCBI Accession: NM_005047, NP_005038

UniProt: Q16401

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway