UNC119B antibody (N-Term)

Catalog No. ABIN2791976

Product Details anti-UNC119B Antibody

Target: UNC119B (Unc-119 Homolog B (UNC119B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC119B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AASAAGPGGL VAGKEEKKKA GGGVLNRLKA RRQAPHHAAD DGVGAAVTEQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against UNC119B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human UNC119B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UNC119B

Target: UNC119B (Unc-119 Homolog B (UNC119B))

Alternative Name: UNC119B (UNC119B Products)

Background: UNC119B is a myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. It binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane. UNC119B does not bind all myristoylated proteins and probably plays a role in trafficking proteins in photoreceptor cells.
Alias Symbols: POC7B
Protein Interaction Partner: UBAC1, RBM8A, SRSF9,
Protein Size: 251

Molecular Weight: 28 kDa

Gene ID: 84747

NCBI Accession: NM_001080533, NP_001074002

UniProt: A6NIH7