SEC13 antibody (Middle Region)

Catalog No. ABIN2792059

Product Details anti-SEC13 Antibody

Target: SEC13 (SEC13 Homolog (SEC13))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC13 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GHEGPVWQVA WAHPMYGNIL ASCSYDRKVI IWREENGTWE KSHEHAGHDS

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SEC13. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SEC13

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SEC13

Target: SEC13 (SEC13 Homolog (SEC13))

Alternative Name: SEC13 (SEC13 Products)

Synonyms: D3S1231E antibody, SEC13L1 antibody, SEC13R antibody, npp-20 antibody, 1110003H02Rik antibody, Sec13l1 antibody, Sec13r antibody, Protein SEC13 homolog antibody, SEC13 homolog, nuclear pore and COPII coat complex component antibody, npp-20 antibody, SEC13 antibody, Sec13 antibody

Background: The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found.
Protein Interaction Partner: SEC16B, UBC, TRAF5, FUS, SUMO2, SUMO1, NEDD8, RNF2, PRPF19, PSMB1, POLR2E, MAPK9, EGFR, BAG3, RAD52, CSNK1E, CSNK1A1, CLDN12, SEC31A, SEC23A, SLC12A2, NUP107, CUL3, STAM2, SIRT7, EBNA-LP, Nup98, NUP145, SEC13, WDR44, RAB11A, NUP160, NUP85, NUP37, NUP133,
Protein Size: 368

Molecular Weight: 40 kDa

Gene ID: 6396

NCBI Accession: NP_001129498

UniProt: B4DXJ1