TAF1A antibody (N-Term)

Catalog No. ABIN2792589

Product Details anti-TAF1A Antibody

Target: TAF1A (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, A, 48kDa (TAF1A))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Horse, Rabbit, Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF1A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CLSFIQEALL KHQWQQAAEY MYSYFQTLED SDSYKRQAAP EIIWKLGSEI

Cross-Reactivity: Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Dog: 92%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 78%, Rabbit: 85%, Rat: 78%

Characteristics: This is a rabbit polyclonal antibody against TAF1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TAF1A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 450 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAF1A

Target: TAF1A (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, A, 48kDa (TAF1A))

Alternative Name: TAF1A (TAF1A Products)

Synonyms: TAFI48 antibody, mTAFI48 antibody, MGC:17061 antibody, RAFI48 antibody, SL1 antibody, TATA-box binding protein associated factor, RNA polymerase I, A antibody, TATA-box binding protein associated factor, RNA polymerase I subunit A antibody, Taf1a antibody, TAF1A antibody

Background: Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, also known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
Alias Symbols: SL1, RAFI48, TAFI48, MGC:17061
Protein Interaction Partner: C11orf57, JMJD6, TBP, Taf1c, Taf1b, BKRF1, UBC, TAF12, TAF1D, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, ESR1, SET, TAF1A, RUNX2, TP53, CD3EAP, HIST4H4, HIST3H3, ANP32A, UBTF, RRN3, MYC,
Protein Size: 450

Molecular Weight: 53 kDa

Gene ID: 9015

NCBI Accession: NM_005681, NP_005672

UniProt: Q15573