CYP21A2 antibody (Center)

Catalog No. ABIN2793266

Product Details anti-CYP21A2 Antibody

Target: CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))

Binding Specificity: AA 216-246, Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP21A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Purpose: Rabbit Anti-Human CYP21A2 (Center) Antibody

Immunogen: This CYP21A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-246 amino acids from the Central region of human CYP21A2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, FC: 1:10-50, IF: 1:10-50Western blot analysis of CYP21A2 Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CYP21A2

Target: CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))

Alternative Name: CYP21A2 (CYP21A2 Products)

Synonyms: CA21H antibody, CAH1 antibody, CPS1 antibody, CYP21 antibody, CYP21B antibody, P450c21B antibody, 21-OH antibody, 21OH antibody, 21OHA antibody, 21OHB antibody, CYP21OH-A antibody, Cyp21 antibody, Cyp21-ps1 antibody, Cyp21B antibody, Cyp21a2-ps antibody, Cyp21a2ps antibody, Oh21-1 antibody, Oh21-2 antibody, CYP21A antibody, 21-OHase antibody, cytochrome P450 family 21 subfamily A member 2 antibody, cytochrome P450, family 21, subfamily a, polypeptide 1 antibody, cytochrome P450c21 antibody, cytochrome P450, family 21, subfamily A, polypepide 2 antibody, cytochrome P450, family 21, subfamily A, polypeptide 2 antibody, steroid 21-hydroxylase-like antibody, CYP21A2 antibody, Cyp21a1 antibody, LOC101094596 antibody

Background:

Target Description: CYP21A2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in CYP21A2 gene cause congenital adrenal hyperplasia.

Gene Symbol: CYP21A2

Molecular Weight: 55887 Da

Gene ID: 1589

UniProt: P08686

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process